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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

A/Prof Aaron Irving

Dr Dieter Bulach

Prof Roger Nation

Dr Kristie Jenkins

Dr Simon Royce

Dr Ben Croker

Prof Michael Hickey

Prof Alister Ward

Prof A Richard Kitching

A/Prof Anna Coussens

Prof Bryan Williams

Prof Stephen Kent

Mrs Sheila Nankoberanyi

Dr Holly Anderton

Dr Latasha Abeynaike

Prof Jason Mackenzie

Dr Jim Harris

A/Prof Dena Lyras

Dr KE TANG

Dr Prasad Paradkar

Dr Jiyao Gan

Dr Howard Yim

Dr Alison West

A/Prof Ashley Mansell

Dr Louis Schofield

Dr Seth Masters

Dr Greg Moseley

Prof Paul Hertzog

Adjunct Prof Kathryn Holt

Dr Alec Drew

Dr Alyssa Barry

A/Prof Kumar Visvanathan

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Associate Professor Michelle Tate

A/Prof Motti Gerlic

Dr Hani Hosseini Far

Dr Matt Firth

Prof Gabrielle Belz

Dr Dominic De Nardo

Dr Bernadette Jones-Freeman

Dr Scott Mueller

Miss Kathryn Prame Kumar

Prof Tim Stinear

Dr Amy Chung

Prof Ana Traven

Dr Thomas Angelovich

Dr Sara Klose

A/Prof Mark Chong

Dr Tom Brodnicki

Prof Jian Li

Ms Sarah Rosli

Dr Nicole De Weerd

Dr Patrick Reading

Dr Kelly Wyres

Dr Ashraful Haque

Ms Caitlin Rowe

Mr Stuart Lee

Prof Bill Heath

Prof Fabienne Mackay

Dr Rebecca Gorrell

Dr Alice West

Dr Kate Jeffrey

Prof Steven Gerondakis