Dr Anna Walduck

Senior Lecturer in Applied Microbiology, Laboratory Head
Biosciences
RMIT University

399257145
anna.walduck@rmit.edu.au

Latest News

Two new ARC funded projects on novel vaccination strategies in poultry: Applicants for PhD positions are being sought. Get in touch for more details!

Research Activities

We are interested in the interactions between host and pathogen in acute and chronic infections.
Including: 
Severe sepsis- Sepsis has a high mortality rate, there is an urgent need for adjunct therapies to improve patient outcomes. We are investigating immunological responses in patients with sepsis and looking at the potentially positive effects of low dose aspirin. This study is supported by experiments in animal and in vitro models of sepsis and biofilm related infections.  

Understanding inflammation in the stomach to guide development of new vaccines against Helicobacter pylori. This bacterium infects up to half of the world population and causes chronic, potentially fatal disease. We are investigating the complex regulation of inflammation in the stomach to understand how to better design vaccines.  

Novel Wound dressings using silver nano-structured fabrics.
In collaboration with Prof. Vipul Bansal's group ( RMIT) we are developing wound infection models to test novel wound dressings based on TCNQ. These fabrics have strong anti-microbial properties and are predicted to also enhance wound healing. See: https://www.rmit.edu.au/news/all-news/2016/april/nano-enhanced-textiles-clean-themselves-with-light/

2018:
Two new projects on novel vaccination strategies in poultry: Applicants for PhD positions are being sought:
1)    Development of methods for the selection and delivery of vaccine antigens and other biologically active proteins using live microbial vectors. This project will design and test antigen expression constructs that will investigate different approaches to deliver multiple antigens in the most effective way, using live microbes as delivery vehicles.  
2)    Development of methods to enhance specific immune responses to vaccine antigens. There are opportunities to improve the effectiveness

Techniques/Expertise

Mouse models of infection
vaccination
 flow cytometry
 immunohistochemistry

Collaborations

Dr Odilia Wijburg
Assoc. Prof Damon Eisen (Victorian Infectious Disease Service), Dr Sukanya Raghavan (University of Gothenburg)
Prof Vipul Bansal & Dr Rajesh Ramanathan ( RMIT NanoBiotechnology Research Lab, Ian Potter NanoBioSensing Facility)

Disease Models

H. pylori mouse model, vaccination
vaccination models in mice using attenuated Salmonella
S. aureus sepsis
Infection models in Leptin deficient mice ( ob/bo & db/db)
 Immune responses to vaccination in poultry

Other Lab Members

Jacinta Ortega ( PhD candidate)
Dipesh Kumar ( Masters by Research)

Research Images

Other members with similar research interests

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A/Prof Phil Sutton

Infection and Immunity Theme Murdoch Childrens Research Institute SEE FULL PROFILE >

A/Prof Kumar Visvanathan

University of Melbourne SEE FULL PROFILE >

Prof James Beeson

Centre for Biomedical Research Burnet Institute SEE FULL PROFILE >

Upcoming Events

  • Feb 14

    Lorne Infection and Immunity Conference 2018

    Cumberland Lorne Resort REGISTER | MORE INFO
  • Mar 1

    18th International Congress on Infectious Diseases

    Sheraton Buenos Aires MORE INFO
  • Mar 15

    Eradicate Cancer 2018

    Melbourne Convention and Exhibition Centre MORE INFO