Mr Dhanasekaran Sakthivel

PhD Student
Department of Biochemistry and Molecular Biology
Monash University

+61 4 1454 7007
dhansay@gmail.com

Research Activities

In my PhD program, I aim to examine the role of carbohydrate recognizing proteins of sheep (galectin 11 and 14 which have novel anti-parasitic activities in resistant animals) and how they interact with glycan’s present on the parasites surface in order to provide better insights in host immune resistance and for the design of a glycan based vaccine

Techniques/Expertise

  • Gene cloning, Protein expression in prokaryote and eukaryote system, Protein purification by various chromatographic approach, Macromolecular structure determination by X-ray crystallography. 
  • Gene expression analysis by quantitative reverse transcription PCR and western blot analysis.  Maintained animal virus (BTV, PPRV and pox) 
  • Handled animal parasites (H. contortus, Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi and F. hepatica)

Disease Models

  • BALB/c mice for the propagation of Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi
  • Chicken for the New castle disease virus vaccine
  • Sheep and goat for the propagation of  H. contortus immune response 
  • Bovine for the vaccine studies of Theileria annulata 

Genetically Modified Organisms

E. coli

Other members with similar research interests

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A/Prof Rosemary Ffrench

Centre for Biomedical Research Burnet Institute SEE FULL PROFILE >

Prof James Beeson

Centre for Biomedical Research Burnet Institute SEE FULL PROFILE >

Prof Ross Coppel

Faculty of Medicine, Nursing and Health Sciences Monash University SEE FULL PROFILE >

Upcoming Events

  • Feb 14

    Lorne Infection and Immunity Conference 2018

    Cumberland Lorne Resort REGISTER | MORE INFO
  • Mar 1

    18th International Congress on Infectious Diseases

    Sheraton Buenos Aires MORE INFO
  • Mar 15

    Eradicate Cancer 2018

    Melbourne Convention and Exhibition Centre MORE INFO