Mr Dhanasekaran Sakthivel

PhD Student
Department of Biochemistry and Molecular Biology
Monash University

+61 4 1454 7007
dhansay@gmail.com

Research Activities

In my PhD program, I aim to examine the role of carbohydrate recognizing proteins of sheep (galectin 11 and 14 which have novel anti-parasitic activities in resistant animals) and how they interact with glycan’s present on the parasites surface in order to provide better insights in host immune resistance and for the design of a glycan based vaccine

Techniques/Expertise

  • Gene cloning, Protein expression in prokaryote and eukaryote system, Protein purification by various chromatographic approach, Macromolecular structure determination by X-ray crystallography. 
  • Gene expression analysis by quantitative reverse transcription PCR and western blot analysis.  Maintained animal virus (BTV, PPRV and pox) 
  • Handled animal parasites (H. contortus, Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi and F. hepatica)

Disease Models

  • BALB/c mice for the propagation of Plasmodium berghei, Plasmodium yoleii, Plasmodium falciparum, plasmodium chabaudi
  • Chicken for the New castle disease virus vaccine
  • Sheep and goat for the propagation of  H. contortus immune response 
  • Bovine for the vaccine studies of Theileria annulata 

Genetically Modified Organisms

E. coli

Other members with similar research interests

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Prof Ross Coppel

Faculty of Medicine, Nursing and Health Sciences Monash University SEE FULL PROFILE >

Prof Stephen Kent

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Prof John Hamilton

Department of Medicine (Royal Melbourne Hospital/Western Hospital) University of Melbourne SEE FULL PROFILE >

Upcoming Events

  • Aug 24

    IgV Annual Scientific Meeting

    Balgownie Estate REGISTER | MORE INFO
  • Sep 25

    Global Virus Network Meeting 2017

    Doherty Institute, Melbourne, Australia MORE INFO
  • Oct 16

    LISSSD 2017

    Sofitel Fiji Resort and Spa MORE INFO