A/Prof Heidi Drummer

Program Director, Disease Eliination
Life Sciences
Burnet Institute

heidi.drummer@burnet.edu.au

"VIIN has allowed me to identify new collaborators and industry partners to conduct my research program. "

Licensing opportunities

Vaccine candidates for HCV



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Contract research opportunities

Capacity to produce recombinant proteins in mammallian systems. Stable cell line development for high level protein production.
ion.
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Latest News

Narasimhulu, VGS, Bellamy-Mcintyre, AK, Laumaea, AE, Lay, CS, Harrison, DN, King, HaD, Drummer, HE & Poumbourios, P, 2018, Distinct functions for the membrane-proximal ectodomain region (MPER) of HIV-1 gp41 in cell-free and cell-cell viral transmission and cell-cell fusion. J Biol Chem, 293, 6099
Lucas, M, Deshpande, P, James, I, Rauch, A, Pfafferott, K, Gaylard, E, Merani, S, Plauzolles, A, Lucas, A, Mcdonnell, W, Kalams, S, Pilkinton, M, Chastain, C, Barnett, L, Prosser, A, Mallal, S, Fitzmaurice, K, Drummer, H, Ansari, MA, Pedergnana, V, Barnes, E, John, M, Kelleher, D, Klenerman, P & Gaudieri, S, 2018, Evidence of CD4(+) T cell-mediated immune pressure on the Hepatitis C virus genome. Sci Rep, 8, 7224
Gu, J, Hardy, J, Boo, I, Vietheer, P, Mccaffrey, K, Alhammad, Y, Chopra, A, Gaudieri, S, Poumbourios, P, Coulibaly, F & Drummer, HE, 2018, Escape of Hepatitis C Virus from Epitope I Neutralization Increases Sensitivity of Other Neutralization Epitopes. J Virol, 92,

Research Activities

We aim to develop novel vaccine candidates for Hepatitis C and HIV and seek to understand mechanisms of viral entry, immune evasion and natural immunity to Hepatitis C.

Techniques/Expertise

Mammalian, insect and bacterial protein expression systems, cell line development, monoclonal antibody production and characterization, single cell B cell isolation and IgG production, evaluation of immune responses to vaccine candidates, virus neutralization assays, protein purification and characterization, structural biology.

Collaborations

Dr Fasseli Coulibaly
Dr Pantelis Poumbourios
Professor Ellie Barnes
A/Prof Joseph Torresi

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