Dr Paul Gilson

Laboratory Head
Centre for Biomedical Research
Burnet Institute

+61 3 8506 2481
gilson@burnet.edu.au

Research Activities

Parasite invasion
Understanding how malaria parasites invade their red blood cell hosts namely, the roles of parasite invasion ligands and cellular signalling events. Invasion ligands and signalling pathways are potential vaccine and drug targets.

Host cell modification
Malaria parasites extensively modify their red blood cell hosts by exporting 100s of proteins into them which help the parasite acquire nutrients to grow fast and to avoid host immunity. Knowing how parasites traffic proteins into their host cells is important because this could be a potential drug target.

Techniques/Expertise

Molecular biology
Engineering transgenic parasites with GFP and luciferase fusion proteins
Mutational analysis of parasites
Fluorescence microscopy, Super-resolution microscopy, Video microscopy
Proteomics, phosphoproteomics

Disease Models

Plasmodium falciparum

Genetically Modified Organisms

Plasmodium falciparum

Other Lab Members

Dr Paul Sanders
Dr Catherine Nie
Dr Greta Weiss
Ms Sarah Charnaud
Ms Katherine Harvey
Prof Brendan Crabb

Other members with similar research interests

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Prof Bill Heath

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Mr Brendan Harney

Swinburne University SEE FULL PROFILE >

Dr Darren Creek

Monash Institute of Pharmaceutical Sciences Monash University SEE FULL PROFILE >

Upcoming Events

  • Feb 14

    Lorne Infection and Immunity Conference 2018

    Cumberland Lorne Resort REGISTER | MORE INFO
  • Mar 1

    18th International Congress on Infectious Diseases

    Sheraton Buenos Aires MORE INFO
  • Mar 15

    Eradicate Cancer 2018

    Melbourne Convention and Exhibition Centre MORE INFO