Prof Ross Coppel

Deputy Dean
Faculty of Medicine, Nursing and Health Sciences
Monash University

+61 3 9902 9147
ross.coppel@monash.edu

Research Activities

Studies on mycobacteria and corynebacteria, including M. avium, M. smegmatis, C. glutamicum. Pathways of bacterial cell wall synthesis, host-pathogen biology including mycobacteria in macrophages, identification of genes involved in resisting phagocytosis. Mechanisms of phagocytosis.
Studies on various aspects of malaria biology. Focussing on asexual stages including proteins of the merozoite surface, the rhoptry and the molecular motor.
Vaccine studies including improved methods of delivery, DNA vaccination, oral immunization, transgenic plants, viral delivery. GMP production of recombinant proteins for human clinical trials.

Techniques/Expertise

Molecular biology, protein expression, immunochemistry, immunofluorescence, protein-protein interactions, microarrays, bacterial genetics, TLC, cell wall analysis, sequencing, bioinformatics, Serology, ELISA, malaria gene knockout, malaria parasite culture, mouse models of malaria infection, malaria growth inhibition assays

Collaborations

Malcolm McConville, University of Melbourne
Christina Mitchell, Monash University
Mark von Itzstein Griffith University
Mohan Narla, New York Blood Centre
Eric Gershwin, UC Davis
Laurie Bannister, London
Prof Magdalena Plebanski
Prof Brian Cooke
CIs of the ARC Centre of Excellence in Structural and Functional Microbial Genetics

Disease Models

Malaria in mice; Plasmodium chabaudi and Plasmodium yoelii

Genetically Modified Organisms

4.1 KO mice
CD36 KO mice
Fcγ KO mice

Other Lab Members

Postdoctoral Scientists:
Paul Crellin
Yoshiki Yamaryo-Botte
Casilda Black
Research Assistants:
Rajini Bramanath
Farida Motorina-Valeeva
PhD and Honours students:
Charles Ma
Megan Rees
David Sheffield
Arek Rainczuk
Brendan Elsworth
Bonnie McIntyre

Other members with similar research interests

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Miss Amanda Woon

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

Dr Odilia Wijburg

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

A/Prof Jason Mackenzie

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

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