Mr Abdalla Ali

PhD Student
Department of Microbiology and Immunology
University of Melbourne

abdallaa@student.unimelb.edu.au

Research Activities

One approach toward eliminating HIV latency is the activation of HIV viral production by latency reversal agents (LRAs) to induce virus mediated cytolysis or clearance through immune recognition (often called “shock and kill”). However, currently available LRAs are not specific for HIV, have off target effects and lack sufficient potency to eliminate infected T- cells. Nanoparticle delivery systems possess several advantages over more traditional drug delivery methods, and could potentially increase potency and reduce toxicity. However, there are challenges for uptake of nanoparticles in non-phagocytic resting T‐cells, the major reservoir of latent HIV.

Techniques/Expertise

Cell culture, flow cytometry, confocal microscopy, nanoparticles fabrication, PCR

Disease Models

HIV latency

Upcoming Events

  • Mar 24

    World Tuberculosis Day

  • Mar 25

    ABCD7 - 7th Australian B Cell Dialogue

    Walter + Eliza Hall Institute MORE INFO
  • Apr 13

    29th European Congress of Clinical Microbiology & Infectious Diseases

    MORE INFO