Mr Albert Garcia Minambres
School of Medicine
Research ActivitiesOne of the most important factors in the worldwide spread of HIV is its enormous genetic variability and rapid evolution, which makes the virus highly adaptable to new hosts and selection pressures. This genetic variability of HIV results from the high recombination and mutation rates of the reverse
transcriptase enzyme, which lacks a proof-reading mechanism, together with high rates of virus replication. My PhD is mainly focused on the study of diversity of HIV generated as a result of sub-optimal drug treatments and I also aim to analyse the differences on recombination and mutation rate in different primary cells.