Prof Brendan Jenkins

Laboratory Head
Centre for Innate Immunity and Infectious Diseases
Hudson Institute of Medical Research

brendan.jenkins@monash.edu

Research Activities

In vivo models assessing the mechanisms by which imbalanced STAT1 and STAT3 signalling from the IL-6 cytokine family common receptor gp130 contribute to inflammation, tumourigenesis, dysregulated lympho-hematopoiesis and bone metabolism

Techniques/Expertise

Gene targeting, mammalian cell culture techniques, immuno-detection techniques (eg immunohistochemistry, ELISA, Western blotting, flow cytometry), quantitative RT-PCR analyses

Collaborations

Simon Jones/Nicholas Topley (Cardiff, UK)
Andrew Robers (WEHI, Melbourne)
Matthias Ernst (Ludwig, Melbourne)
Robyn Starr (St Vincents Institute, Melbourne)
Matthew Gillespie and Jack Martin (St Vincents Institute, Melbourne)
Jane Armes (Mater Hospital, Brisbane)

Disease Models

Inflammation (peritonitis, endotoxic shock), gastric cancer, hematopoietic (spenomegaly, thrombocytosis) and lymphoid (lymphadenopathy) disorders , dysregulated bone metabolism.

Genetically Modified Organisms

gp130 knock-in mouse mutants crossed with STAT1/3, IL-6 and IL-11R KO mice

Other Lab Members

2 Research Assistants and 1 UROP student

Other members with similar research interests

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Dr Rob Bischof

Hudson Institute of Medical Research SEE FULL PROFILE >

A/Prof Richard Ferrero

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Dr Alec Drew

Nexvet SEE FULL PROFILE >

Upcoming Events

  • Aug 5

    Australasian Viral Hepatitis Elimination Conference 2019

    Novotel Sydney Brighton Beach, Brigton-Le-Sands MORE INFO
  • Aug 13

    International Veterinary Immunology Symposium (IVIS) 2019

    Renaissance Seattle Hotel 515 Madison Street, Seattle, Washington 98104, USA MORE INFO
  • Aug 26

    Student Open Day Hudson Institute of Medical Research

    Hudson Institute of Medical Research and Monash University MORE INFO