Mrs Sheila Nankoberanyi

Clinical Research Coordinator
Baker IDI Heart and Diabetes Institute

s.nankoberanyi@nucleusnetwork.com.au

Research Activities

I have previously worked with P. Falciparum malaria in collaboration with a group from University of California San Francisco, specifically studying drug resistance & genetic factors underlying treatment outcomes in Uganda. To this end, I evaluated a high throughput genotypic technique for surveillance of SNPs mediating drug resistance; and characterized the distribution of markers & their clinical relevance. And we managed to publish three papers out of this work, which can be accessed online. To date I have expanded my interests to Onchocerciasis eradication through novel molecular and genomic tools. Here we aim to develop novel diagnostic tools for onchocerciasis & identify genetic markers for disease surveillance across different epidemiological zones. So far, I have developed a Loop mediated isothermal amplification (LAMP) assay for point of care applications with regards to onchocerciasis. Cumulatively, I have gained a lot of experience in molecular epidemiology specifically employing state of the art genomic tools to solve prominent infectious disease problems.

Techniques/Expertise

Molecular epidemiology, drug resistance, nematode genomics, assay development, next generation sequencing, translation research

Collaborations

University of California San Fransisco
WHO/TDR
Diagnostics For All

Disease Models

C. elegans for Alzheimer’s disease
Bush Rats for Onchocerciasis pathophysiology studies
Possums for parasite evolution studies

Other members with similar research interests

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Dr Grant Jenkin

Department of Microbiology Monash University SEE FULL PROFILE >

Prof Tim Stinear

Department of Microbiology and Immunology University of Melbourne SEE FULL PROFILE >

Dr Anjaleena Anthony

Promega Corporation SEE FULL PROFILE >

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