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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Howard Yim

Dr Louis Schofield

Dr Wenyi Li

Adjunct Prof Kathryn Holt

Dr Jiyao Gan

Prof Steven Gerondakis

Prof Fabienne Mackay

Dr Alec Drew

Dr Helen Stoelting

Prof Michael Hickey

Dr Ben Croker

Prof Tim Stinear

Prof Bryan Williams

Dr Patrick Reading

Miss Rachel Webb

Prof Bill Heath

Dr Alison West

Dr Hani Hosseini Far

Ms Caitlin Rowe

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Holly Anderton

Miss Vik Ven Eng

Dr Latasha Abeynaike

Dr Scott Mueller

Ms Antara Ghoshal

Dr Sara Klose

Dr Tony Sadler

Dr Sammy Bedoui

Dr Carla Bianca Victorio

Dr Greg Moseley

Prof Gabrielle Belz

Dr Marina Harper

A/Prof Aaron Irving

Prof A Richard Kitching

Dr Ashraful Haque

Dr Matt Firth

Dr Jim Harris

Prof Jian Li

Prof Roger Nation

Dr Le Son Tran

Miss Alessandra Gatta

Dr Rebecca Gorrell

A/Prof Mark Chong

Ms Madeleine Wemyss

Dr Prasad Paradkar

Prof Alister Ward

Prof Stephen Kent

Dr Kate Jeffrey

Mr Stuart Lee

Dr KE TANG

Prof Di Yu

Prof Jason Mackenzie

Dr Kelly Wyres

Prof Ana Traven

Dr Keith Al-Hasani

Dr Thomas Angelovich

Dr Dieter Bulach

Prof Paul Hertzog

Dr Seth Masters

A/Prof Anna Coussens

Dr Rhys Allan

Dr Kristie Jenkins

Dr Tom Brodnicki