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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Holly Anderton

Prof Steven Gerondakis

Ms Madeleine Wemyss

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Keith Al-Hasani

Dr Rhys Allan

Dr Prasad Paradkar

Prof Stephen Turner

A/Prof Aaron Irving

Ms Antara Ghoshal

Dr Dieter Bulach

Prof A Richard Kitching

Dr Thomas Angelovich

Dr Ashraful Haque

Prof Bryan Williams

Miss Kathryn Prame Kumar

Dr Nicole De Weerd

Prof Fabienne Mackay

Dr Alison West

Dr Catherine Kennedy

Dr Jiyao Gan

Dr Matt Firth

Dr KE TANG

Dr Sara Klose

Dr Helen Stoelting

Mrs Sheila Nankoberanyi

Dr Kelly Wyres

Dr Bernadette Jones-Freeman

Dr Tom Brodnicki

A/Prof Motti Gerlic

Prof Roger Nation

Associate Professor Michelle Tate

Prof Bill Heath

Dr Louis Schofield

Dr Hani Hosseini Far

Dr Rebecca Gorrell

Dr Alice West

A/Prof Michael Gantier

Prof Gabrielle Belz

Dr Tony Sadler

Dr Patrick Reading

A/Prof Anna Coussens

Prof Paul Hertzog

Miss Rachel Peiris

Prof Jason Mackenzie

Prof Di Yu

Ms Sarah Rosli

Dr Grant Jenkin

Dr Niamh Mangan

Prof Ana Traven

A/Prof Mark Chong

Dr Howard Yim

Prof Michael Hickey

Miss Vik Ven Eng

Prof Alister Ward

Dr Jim Harris

A/Prof Kumar Visvanathan

Prof Jian Li

Dr Scott Mueller

Dr Wenyi Li

A/Prof Dena Lyras

Dr Boris Novakovic

Dr Marina Harper