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Prof Alex Andrianopoulos

Laboratory Head
School of BioSciences
University of Melbourne

alex.a@unimelb.edu.au

Research Activities

We are studying a number of aspect of T. marneffei biology and pathogenicity and are particularly interested in understanding the molecular mechanisms which control the dimorphic switching and asexual development (conidiation) programs. Dimorphic switching is a temperature- and host-dependent response that allows T. marneffei to switch from a non-pathogenic hyphal growth form to the pathogenic yeast form. The yeast form is specialized to survive with host innate immune cells. Asexual development is the program the produce asexual spores, the infectious particles. We are teasing up the mechanisms that control these programs and examining their effects on growth and pathogenesis in the host.

Research Keywords

Researching in the following areas: Fungal pathogens, Innate immunity, Genomics, Animal Models - Zebrafish, Animal models - Mice

Techniques/Expertise

DNA-protein interactions, genomics, transcriptomics

Disease Models

Macrophage cells, zebrafish, mice

Genetically Modified Organisms

Talaromyces marneffei (formerly Penicillium marneffei), Aspergillus fumigatus, Aspergillus nidulans

Websites

biosciences.unimelb.edu.au/research/research-clusters/genetics-genomics-and-development/

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Prof Alex Andrianopoulos

Research Activities

Research Keywords

Techniques/Expertise

Disease Models

Genetically Modified Organisms

Websites

Other members with similar research interests

Dr Alec Drew

Dr Jim Harris

Dr Patrick Reading

Miss Alessandra Gatta

Prof Jason Mackenzie

A/Prof Ashley Mansell

Dr Wenyi Li

Prof A Richard Kitching

Dr Kate Jeffrey

Prof Fabienne Mackay

Dr Dieter Bulach

Miss Kathryn Prame Kumar

Dr Matt Firth

Prof Roger Nation

Dr Alyssa Barry

Prof Bill Heath

Dr Marina Harper

A/Prof Mark Chong

Ms Sarah Rosli

A/Prof Aaron Irving

Ms Antara Ghoshal

Dr Dominic De Nardo

Prof Stephen Kent

Dr Kristie Jenkins

Dr KE TANG

Mr Stuart Lee

Dr Louis Schofield

A/Prof Motti Gerlic

Prof Paul Hertzog

Dr Niamh Mangan

A/Prof Anna Coussens

Prof Gabrielle Belz

Prof Jamie Rossjohn FAA FLSW FAHMS FMedSci

Dr Jiyao Gan

Dr Carla Bianca Victorio

Dr Simon Royce

Dr Latasha Abeynaike

Prof Bryan Williams

Miss Michelle Clark

Ms Caitlin Rowe

Dr Boris Novakovic

Dr Alison West

A/Prof Michael Gantier

Dr Ben Croker

Ms Madeleine Wemyss

Associate Professor Michelle Tate

Prof Di Yu

Dr Hani Hosseini Far

A/Prof Kumar Visvanathan

Dr Howard Yim

Dr Holly Anderton

Dr Ashraful Haque

Prof Steven Gerondakis

Dr Amy Chung

Dr Greg Moseley

Dr Le Son Tran

Miss Rachel Peiris

Dr Catherine Kennedy

Prof Jian Li

Dr Seth Masters

Dr Kelly Wyres

Dr Alice West

Miss Vik Ven Eng