Dr Boris Novakovic

Team Leader / Senior Research Officer
Cell Biology
Murdoch Childrens Research Institute

boris.novakovic@mcri.edu.au

Research Activities

I am a trained molecular biologist with an interest in epigenetics of human immune cell function and disease. I am particularly interested in applying complementary epigenetic techniques to profile different aspects of chromatin structure and to integrate these data to explain biology. I have experience in the generation and analysis of comprehensive epigenomics data on human primary monocytes, including ChIP, ATAC, and RNA-seq. I gained these skills during a 4 year postdoc in the lab of Prof Hendrik Stunnenberg at Radboud University (Nijmegen, The Netherlands), working on the EU funded BLUEPRINT project, which is part of the International Human Epigenome Consortium (IHEC). Such analysis has resulted in two publications in Cell and other leading journals in the field of immunology. These publications were the result of a close collaboration with the lab of Professor Mihai Netea, the pioneer in the field of ‘trained immunity’. In 2018 I joined MCRI as a Senior Research Officer ‘team leader’ in the lab of Professor Richard Saffery. I am currently using epigenomic techniques to study innate immunity, and have ongoing collaborations with researchers in the Netherlands and recently established collaborations with researchers in Australia to study the molecular events in a variety of human immune diseases.

Techniques/Expertise

RNA-sequencing, ChIP-sequencing, ATAC-seq, DNA methylation, monocyte culture

Collaborations

Prof Mihai Netea (Nijmegen, The Netherlands)
Prof Dave Burgner (MCRI, Melbourne)
Prof Nigel Curtis (MCRI, Melbourne)
Dr Debby van Riel (Erasmus MC, The Netherlands)
Prof Katie Flanagan (U Tasmania, Australia)
Dr Melanie Neeland (MCRI, Melbourne)
Dr Sebastian Weis (Jena, Germany)

Disease Models

Childhood infection, allergy, obesity, human vaccination trials

Other Lab Members

Bowon Kim
Rebecca Shepherd
Samira Imran
Sachintha Wijegunasekara

Other members with similar research interests

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Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

Prof Paul Hertzog

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Dr Le Son Tran

Centre for Innate Immunity and Infectious Diseases Hudson Institute of Medical Research SEE FULL PROFILE >

Upcoming Events

  • Jul 28

    World Hepatitis Day

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  • Aug 16

    12th Australasian Viral Hepatitis Conference

    The Sofitel Brisbane MORE INFO
  • Aug 23

    19th International Symposium on Staphylococci and Staphylococcal Infections

    Perth Convention and Exhibition Centre MORE INFO