A/Prof Dena Lyras

Senior Lecturer
Department of Microbiology
Monash University

+61 3 9902 9155
dena.lyras@monash.edu

Research Activities

Clostridial pathogenesis, particularly involving Clostridium perfringens, Clostridium difficile and Clostridium sordellii, including both animal and human strains. Spores and biofilms of the clostridia. Biology of clostridial transposons. Antibiotic resistance and horizontal gene transfer.

Techniques/Expertise

Microbial Genetics

Collaborations

Dr John Emmins, Department of Immunology, Monash University (Clostridium perfringens and Clostridium septicum pathogenesis; mouse model of disease).
Dr Grant Jenkin, Infectious Diseases Physician, Director of Tuberculosis Service, Monash Medical Centre (Clostridium difficile identification and epidemiology)
Dr Peter Mullany, Division of Microbial Diseases, UCL Eastman Dental Institute, UK (Mobile genetic elements)
Dr Adam Roberts, Division of Microbial Diseases, UCL Eastman Dental Institute, UK (Mobile genetic elements)
Dr Bruno Dupuy, Institut Pasteur, France (Clostridium difficile regulation and pathogenesis)
Dr Gill Douce, University of Glasgow, UK (Clostridium difficile pathogenesis, hamster disease model)
Dr Stuart Johnson, Loyola University, Chicago, USA (Clostridium difficile pathogenesis; hamster disease model)
Professor Dale Gerding, Loyola University, Chicago, USA (Clostridium difficile pathogenesis; hamster disease model)
Professor Thomas Riley, The University of Western Australia (Clostridium difficile epidemiology; Clostridium difficile in livestock animals)
Professor J. Glenn Songer, University of Arizona, USA (Clostridium difficile spores and epidemiology; Clostridium difficile in livestock animals)
Dr David Aronoff, Department of Internal Medicine, University of Michigan Health System, USA (Clostridium sordellii pathogenesis; rat disease model)
Professor Neil Fairweather, Imperial College, London, UK (Clostridium difficile surface structures).
Professor Jon Brazier, Anaerobe Reference Laboratory, Cardiff, UK (studies on Fusobacterium necrophorum)
Prof Julian Rood
Dr Grant Jenkin

Disease Models

Mouse model of clostridial myonecrosis
Mouse model of Clostridium difficile disease

Other Lab Members

HONOURS STUDENTS
Ed Rose
PhD STUDENTS
David Kim
Joanne Wee
Anjana Chakravorty
Kate Mackin
RESEARCH ASSISTANTS
Julie Singleton
Pauline Howarth
POST DOCS
Michelle Kelly
Milena Awad
Dr Glen Carter

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