Prof Elizabeth Hartland

Director
Hudson Institute of Medical Research

+61 3 8572 2700
elizabeth.hartland@hudson.org.au

Research Activities

Research in our laboratory is focused on the identification of new virulence determinants in the bacterial pathogens, enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC) and Legionella. A major aim of this research is to investigate the interaction of novel virulence factors with host cell proteins and in particular to establish the biochemical and molecular basis of their role in pathogenesis. Our long term goal is to uncover new host processes and structures that are targeted by bacteria during infection leading to the design and development of novel anti-infective agents to treat a range of infectious diseases.

Techniques/Expertise

Genetic manipulation of bacterial pathogens
In vivo models of infection
Protein-protein interactions
Host-pathogen imaging
Innate immune signalling
Effector protein biochemistry

Collaborations

John Silke, WEHI
Andreas Strasser, WEHI
Gad Frankel, Imperial College London
Professor Ian van Driel, University of Melbourne
Professor Carmen Buchrieser, Institute Pasteur

Disease Models

Mouse model of Legionnaire's disease
Mouse model of diarrhoea 
Mouse model of inflammatory bowel disease

Research Images

Other members with similar research interests

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Dr Natalie Borg

Department of Biochemistry and Molecular Biology Monash University SEE FULL PROFILE >

A/Prof Jan Tennent

Biomedical Research Victoria SEE FULL PROFILE >

A/Prof David Piedrafita

Federation University SEE FULL PROFILE >

Upcoming Events

  • Feb 14

    Lorne Infection and Immunity Conference 2018

    Cumberland Lorne Resort REGISTER | MORE INFO
  • Mar 1

    18th International Congress on Infectious Diseases

    Sheraton Buenos Aires MORE INFO
  • Mar 15

    Eradicate Cancer 2018

    Melbourne Convention and Exhibition Centre MORE INFO