Prof Elizabeth Hartland

Director
Hudson Institute of Medical Research

+61 3 8572 2700
elizabeth.hartland@hudson.org.au

Research Activities

Research in our laboratory is focused on the identification of new virulence determinants in the bacterial pathogens, enteropathogenic and enterohemorrhagic E. coli (EPEC and EHEC) and Legionella. A major aim of this research is to investigate the interaction of novel virulence factors with host cell proteins and in particular to establish the biochemical and molecular basis of their role in pathogenesis. Our long term goal is to uncover new host processes and structures that are targeted by bacteria during infection leading to the design and development of novel anti-infective agents to treat a range of infectious diseases.

Techniques/Expertise

Genetic manipulation of bacterial pathogens
In vivo models of infection
Protein-protein interactions
Host-pathogen imaging
Innate immune signalling
Effector protein biochemistry

Collaborations

John Silke, WEHI
Andreas Strasser, WEHI
Gad Frankel, Imperial College London
Professor Ian van Driel, University of Melbourne
Professor Carmen Buchrieser, Institute Pasteur

Disease Models

Mouse model of Legionnaire's disease
Mouse model of diarrhoea 
Mouse model of inflammatory bowel disease

Research Images

Other members with similar research interests

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Ms Stephanie Trend

School of Paediatrics and Child Health University of Western Australia SEE FULL PROFILE >

Dr Mark Wickham

Chemistry and Life Sciences Phillips Ormonde Fitzpatrick SEE FULL PROFILE >

Dr Grant Jenkin

Department of Microbiology Monash University SEE FULL PROFILE >

Upcoming Events

  • Oct 29

    Cytokines 2017

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  • Nov 1

    12th AUSTRALIAN INFLUENZA SYMPOSIUM 2017

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  • Nov 2

    Australian Respiratory Virology Meeting

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