Dr Philippe Boeuf

Senior Research Officer
Centre for Biomedical Research
Burnet Institute

philippe.boeuf@burnet.edu.au

Research Activities

Research in our laboratory is focused on the pathogenesis of human malaria, in particular of malaria in pregnancy. A major aim of this research is to investigate the interaction Plasmodium falciparum-infected erythrocytes with host cells and tissues, with a focus on the placenta and maternal monocytes. Our long-term goal is to uncover mechanisms of disease and correlates of protection to inform the design and development of novel intervention strategies to alleviate the burden of malaria in pregnancy.

Techniques/Expertise

  • Plasmodium falciparum-infected erythrocytes placental adhesion assay using flow cytometry
  • Flow cytometric analysis of levels of antibodies to surface antigens of Plasmodium falciparum-infected erythrocytes
  • Real time quantitative PCR-based quantification of cytokine gene expression
  • Immunohistochemical analysis of placental tissue
  • Amino acid uptake by placental tissue or placental cell lines

Collaborations

Dr Jocelyn Glazier, The University of Manchester, UK
A/Pr Ali Salanti, Centre for Medical Parasitology, Copenhagen, Denmark
Pr Lars Hviid, Centre for Medical Parasitology, Copenhagen, Denmark
Pr Stefan Magez, VIB, Brussels, Belgium
A/Prof Thomas Jansson, UTHSCSA, USA
Prof Philippe Deloron, IRD, France

Websites

burnet.edu.au

Other Lab Members

Genelyn Dimasuay
Prof James Beeson

Research Images

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