Prof Ross Coppel
Deputy Dean
Faculty of Medicine, Nursing and Health Sciences
Monash University
ross.coppel@monash.edu
Research Activities
Studies on mycobacteria and corynebacteria, including M. avium, M. smegmatis, C. glutamicum. Pathways of bacterial cell wall synthesis, host-pathogen biology including mycobacteria in macrophages, identification of genes involved in resisting phagocytosis. Mechanisms of phagocytosis.Studies on various aspects of malaria biology. Focussing on asexual stages including proteins of the merozoite surface, the rhoptry and the molecular motor.
Vaccine studies including improved methods of delivery, DNA vaccination, oral immunization, transgenic plants, viral delivery. GMP production of recombinant proteins for human clinical trials.
Techniques/Expertise
Molecular biology, protein expression, immunochemistry, immunofluorescence, protein-protein interactions, microarrays, bacterial genetics, TLC, cell wall analysis, sequencing, bioinformatics, Serology, ELISA, malaria gene knockout, malaria parasite culture, mouse models of malaria infection, malaria growth inhibition assaysCollaborations
Malcolm McConville, University of MelbourneChristina Mitchell, Monash University
Mark von Itzstein Griffith University
Mohan Narla, New York Blood Centre
Eric Gershwin, UC Davis
Laurie Bannister, London
Prof Magdalena Plebanski
Prof Brian Cooke
CIs of the ARC Centre of Excellence in Structural and Functional Microbial Genetics
Disease Models
Malaria in mice; Plasmodium chabaudi and Plasmodium yoeliiGenetically Modified Organisms
4.1 KO miceCD36 KO mice
Fcγ KO mice
Other Lab Members
Postdoctoral Scientists:Paul Crellin
Yoshiki Yamaryo-Botte
Casilda Black
Research Assistants:
Rajini Bramanath
Farida Motorina-Valeeva
PhD and Honours students:
Charles Ma
Megan Rees
David Sheffield
Arek Rainczuk
Brendan Elsworth
Bonnie McIntyre
